Article
Improving ethanol and xylitol fermentation at elevated temperature through substitution of xylose reductase in Kluyveromyces marxianus.
Journal of industrial microbiology & biotechnology - 1 Apr 2013
Zhang Biao, Li Lulu, Zhang Jia, Gao Xiaolian, Wang Dongmei, Hong Jiong
Abstract excerpt
Thermo-tolerant yeast Kluyveromyces marxianus is able to utilize a wide range of substrates, including xylose; however, the xylose fermentation ability is weak because of the redox imbalance under oxygen-limited conditions. Alleviating the intracellular redox imbalance through engineering the coenzyme specificity of NADPH-preferring xylose reductase (XR) and improving the expression of XR should promote xylose...
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