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Article

Different transcriptional responses of haploid and diploid S. cerevisiae strains to changes in cofactor preference of XR.

Microbial cell factories - 13 Nov 2020

Xie Cai-Yun, Yang Bai-Xue, Song Qing-Ran, Xia Zi-Yuan, Gou Min, Tang Yue-Qin

Abstract excerpt

BACKGROUND: Xylitol accumulation is a major barrier for efficient ethanol production through heterologous xylose reductase-xylitol dehydrogenase (XR-XDH) pathway in recombinant Saccharomyces cerevisiae. Mutated NADH-preferring XR is usually employed to alleviate xylitol accumulation. However, it remains unclear how mutated XR affects the metabolic network for xylose metabolism. In this study, haploid and diploid...

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Identifiers

PMID: 33187525
DOI: 10.1186/s12934-020-01474-2
PMCID: PMC7666519

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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