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Article

Human embryonic stem cell-derived cardiomyocytes: demonstration of a portion of cardiac cells with fairly mature electrical phenotype.

Experimental biology and medicine (Maywood, N.J.) - 1 Apr 2010

Pekkanen-Mattila Mari, Chapman Hugh, Kerkelä Erja, Suuronen Riitta, Skottman Heli, Koivisto Ari-Pekka, Aalto-Setälä Katriina

Abstract excerpt

Cardiomyocytes (CMs) derived from human embryonic stem cells (hESC) provide a promising tool for the pharmaceutical industry. In this study the electrical properties and maturation of hESC-CM derived using two differentiation methods were compared and the suitability of hESC-CMs as a cell model for the assessment of drug-induced repolarization delay was evaluated. CMs were differentiated either in END-2...

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Identifiers

PMID: 20407085
DOI: 10.1258/ebm.2010.009345

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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