Article
In vivo differentiation of induced pluripotent stem cell-derived cardiomyocytes.
Circulation journal : official journal of the Japanese Circulation Society - 1 Jan 2013
Yu Tao, Miyagawa Shigeru, Miki Kenji, Saito Atsuhiro, Fukushima Satsuki, Higuchi Takahiro, Kawamura Masashi, Kawamura Takuji, Ito Emiko, Kawaguchi Naomasa, Sawa Yoshiki, Matsuura Nariaki
Abstract excerpt
BACKGROUND: Induced pluripotent stem cells (iPSCs) hold promise for a new era in treating heart failure. However, the functional microstructure of iPSC-derived cardiomyocytes (iPSC-CMs) and their ability to attach to the extracellular matrix of the recipient myocardium require further elucidation. Thus, we analyzed the functional microstructure and adhesion molecules of iPSC-CM. METHODS AND RESULTS:...
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