Article
The genetics of Parkinson's disease: progress and therapeutic implications.
Movement disorders : official journal of the Movement Disorder Society - 1 Jan 2013
Singleton Andrew B, Farrer Matthew J, Bonifati Vincenzo
Abstract excerpt
The past 15 years has witnessed tremendous progress in our understanding of the genetic basis for Parkinson's disease (PD). Notably, whereas most mutations, such as those in SNCA, PINK1, PARK2, PARK7, PLA2G6, FBXO7, and ATP13A2, are a rare cause of disease, one particular mutation in LRRK2 has been found to be common in certain populations. There has been considerable progress in finding risk loci. To date,...
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