Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Robust shifts in S100a9 expression with aging: A novel mechanism for chronic inflammation

5 Feb 2013

Abstract excerpt

The S100a8 and S100a9 genes encode a pro-inflammatory protein (calgranulin) that has been implicated in multiple diseases. However, involvement of S100a8/a9 in the basic mechanisms of intrinsic aging has not been established. In this study, we show that shifts in the abundance of S100a8 and S100a9 mRNA are a robust feature of aging in mammalian tissues, involving a range of cell types including the central...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Coagulation and Thrombosis Mechanisms
Share to Immune Response and Inflammation
Share to S100 Proteins and Annexins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23386971
DOI: 10.1038/srep01215

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Robust shifts in S100a9 expression with aging: A novel mechanism for chronic inflammationPMID 23386971Read ↗

C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9Semantic proximity Read ↗

C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100A8 and S100A9Semantic proximity Read ↗

The S100 family is a prognostic biomarker and correlated with immune cell infiltration in pan-cancerSemantic proximity Read ↗

The Calcium Binding Protein S100A11 and Its Roles in DiseasesSemantic proximity Read ↗

Elucidating the pan-oncologic landscape of S100A9: prognostic and therapeutic corollaries from an integrative bioinformatics and Mendelian randomization analysis.Semantic proximity Read ↗

The role of S100A9 in the progression of tuberculosisSemantic proximity Read ↗

Transcriptional activation of Jun and Fos members of the AP-1 complex is a conserved signature of immune aging that contributes to inflammagingSemantic proximity Read ↗

A Generally Applicable Translational Strategy Identifies S100A4 as a Candidate Gene in AllergySemantic proximity Read ↗

Identifying gene expression profiles associated with neurogenesis and inflammation in the human subependymal zone from development through agingSemantic proximity Read ↗

AP-1 complex activation is a conserved signature of immune system aging and a potential regulator of inflammaging in human and miceSemantic proximity Read ↗

Transcription Factor Repertoire of Homeostatic EosinophilopoiesisSemantic proximity Read ↗

Human patient-specific FOXG1 syndrome mouse model revealed FOXG1-MYCN-mediated regulation of protein homeostasis in neurodevelopmental disorderSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.