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Transcription Factor Repertoire of Homeostatic Eosinophilopoiesis

12 Aug 2015

Abstract excerpt

The production of mature eosinophils (Eos) is a tightly orchestrated process with the aim to sustain normal Eos levels in tissues while also maintaining low numbers of these complex and sensitive cells in the blood. To identify regulators of homeostatic eosinophilopoiesis in mice, we took a global approach to identify genome-wide transcriptome and epigenome changes that occur during homeostasis at critical...

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Share to Eosinophilic Disorders and Syndromes
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PMID: 26268651
DOI: 10.4049/jimmunol.1500510

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