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Article

Analysis of ADRB2 (Arg16Gly) Gene Variant with Susceptibility, Pharmacogenetic Response and Disease Severity in South Indian Asthmatics.

Inflammation - 1 Dec 2015

Bandaru Srinivas, Akka Jyothy, Marri Vijaya Kumar, Alvala Mallika, Ponnala Deepika, Mundluru Hema Prasad

Abstract excerpt

β2-Adrenergic receptor (β2-AR) plays a crucial role in asthma pathophysiology by regulating, processes of the lung function, and clinical response to bronchodilators. The +46G>A- Gly16Arg polymorphism in the gene encoding β2 adrenergic receptor (ADRB2) has been associated with receptor non-responsiveness after β2-agonist exposure. In the present study, we sought to evaluate the possible association of Gly16Arg...

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Identifiers

PMID: 26071206
DOI: 10.1007/s10753-015-0197-y

Genes

ADRB2

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