Associations of ATG7 rs1375206 polymorphism and elevated plasma ATG7 levels with late-onset sporadic Parkinson's disease in a cohort of Han Chinese from southern China.

doi:10.1080/00207454.2020.1731507

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Article

Associations of ATG7 rs1375206 polymorphism and elevated plasma ATG7 levels with late-onset sporadic Parkinson's disease in a cohort of Han Chinese from southern China.

The International journal of neuroscience - 1 Dec 2020

Zhao Xiyao, Chen Yusen, Wang Li, Li Xiangxin, Chen Xiaoyi, Zhang Hao

Abstract excerpt

Background: Autophagy-related gene 7 (ATG7) plays a key role in autophagy and is strongly implicated in Parkinson's disease (PD). This study investigated the associations of rs1375206 polymorphism in ATG7 gene promoter and plasma ATG7 levels with late-onset sporadic PD in a cohort of Han Chinese from southern China.Methods: Variant genotypes were identified using polymerase chain reaction-restriction fragment...

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PMID: 32065549
DOI: 10.1080/00207454.2020.1731507

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