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Recent advances in understanding the molecular mechanisms of the development and function of <scp>T</scp>h17 cells

5 Feb 2013

Abstract excerpt

IL-17-producing T helper (Th17) cells comprise a distinct Th subset involved in epithelial cell- and neutrophil-mediated immune responses against extracellular microbes. At the same time, Th17 cells play significant roles in the development of autoimmune diseases including rheumatoid arthritis and multiple sclerosis. Since the identification of Th17 cells approximately a decade ago, the molecular mechanisms of...

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PMID: 23383714
DOI: 10.1111/gtc.12039

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