Article
FADS gene polymorphisms confer the risk of coronary artery disease in a Chinese Han population through the altered desaturase activities: based on high-resolution melting analysis.
PloS one - 1 Jan 2013
Li Si-Wei, Lin Kun, Ma Pei, Zhang Zhen-Lu, Zhou Yi-Dan, Lu Shuang-Yan, Zhou Xin, Liu Song-Mei
Abstract excerpt
OBJECTIVE: We explored the desaturase activities and the correlation of fatty acid desaturases (FADS) gene single nucleotide polymorphisms (SNPs) with plasma fatty acid in coronary artery disease (CAD) patients in a Chinese Han population. METHODS: Plasma fatty acids were measured by gas chromatography in CAD patients (n = 505) and a control group (n = 510). Five SNPs in the FADS gene were genotyped with...
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