Article
Polymorphisms in FADS1 and FADS2 alter plasma fatty acids and desaturase levels in type 2 diabetic patients with coronary artery disease.
Journal of translational medicine - 22 Mar 2016
Li Si-Wei, Wang Jin, Yang Ying, Liu Zhi-Jie, Cheng Lin, Liu Huan-Yu, Ma Pei, Luo Wan, Liu Song-Mei
Abstract excerpt
BACKGROUND: To explore whether plasma fatty acids and SNPs in the fatty acid desaturase (FADS) gene associated with type 2 diabetes (T2D) and coronary artery disease (CAD). METHODS: In this cross-sectional study, we utilized gas chromatography-mass spectrometric analysis and the high-resolution melting method to detect plasma fatty acids and SNPs respectively (rs174537G>T, rs174616C>T, rs174460T>C, and...
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