Article
Association of genetic polymorphisms in matrix metalloproteinase-9 and coronary artery disease in the Chinese Han population: a case-control study.
Genetic testing and molecular biomarkers - 1 Sept 2013
Wu Hai-di, Bai Xiao, Chen Dong-mei, Cao Hong-yan, Qin Ling
Abstract excerpt
OBJECTIVE: Matrix metalloproteinase-9 (MMP-9) plays an important role in inflammation and matrix degradation involved in atherosclerosis and plaque rupture. The T allele of rs3918242 has been reported to lead to a high promoter activity and associate with the extent of coronary artery disease (CAD). And some studies have reported that the G allele of rs17576 might be associated with CAD. The aim of this study was...
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