Article
Eukaryotic TPP riboswitch regulation of alternative splicing involving long-distance base pairing.
Nucleic acids research - 1 Mar 2013
Li Sanshu, Breaker Ronald R
Abstract excerpt
Thiamin pyrophosphate (TPP) riboswitches are found in organisms from all three domains of life. Examples in bacteria commonly repress gene expression by terminating transcription or by blocking ribosome binding, whereas most eukaryotic TPP riboswitches are predicted to regulate gene expression by modulating RNA splicing. Given the widespread distribution of eukaryotic TPP riboswitches and the diversity of their...
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