Article
Thiamine biosynthesis in algae is regulated by riboswitches.
Proceedings of the National Academy of Sciences of the United States of America - 26 Dec 2007
Croft Martin T, Moulin Michael, Webb Michael E, Smith Alison G
Abstract excerpt
In bacteria, many genes involved in the biosynthesis of cofactors such as thiamine pyrophosphate (TPP) are regulated by ribo switches, regions in the 5' end of mRNAs to which the cofactor binds, thereby affecting translation and/or transcription. TPP riboswitches have now been identified in fungi, in which they alter mRNA splicing. Here, we show that addition of thiamine to cultures of the model green alga...
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