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Article

Realgar bioleaching solution is a less toxic arsenic agent in suppressing the Ras/MAPK pathway in Caenorhabditis elegans.

Environmental toxicology and pharmacology - 1 Mar 2013

Liu Dongling, Zhi Dejuan, Zhou Ting, Yu Qinghong, Wan Fengqi, Bai Yanli, Li Hongyu

Abstract excerpt

To explore other arsenic derivatives with anticancer effects and fewer adverse effects, realgar bioleaching solution (RBS) has been found to be a viable approach. Here we used C. elegans as a model organism to its possible efficacy for anti-cancer effect of RBS. Our results indicated that RBS significantly suppressed the multivulva (Muv) phenotype of let-60 ras(gf) mutant that was positive correlated to arsenic...

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PMID: 23376179
DOI: 10.1016/j.etap.2013.01.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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