Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Family of Indoles Regulate Virulence and Shiga Toxin Production in Pathogenic E. coli

23 Jan 2013

Abstract excerpt

Enteropathogenic Escherichia coli (EPEC), enterohemorrhagic E. coli (EHEC) and enteroaggregative E. coli (EAEC) are intestinal pathogens that cause food and water-borne disease in humans. Using biochemical methods and NMR-based comparative metabolomics in conjunction with the nematode Caenorhabditis elegans, we developed a bioassay to identify secreted small molecules produced by these pathogens. We identified...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Escherichia coli research studies
Share to Gut microbiota and health
Share to Viral gastroenteritis research and epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23372726
DOI: 10.1371/journal.pone.0054456

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Family of Indoles Regulate Virulence and Shiga Toxin Production in Pathogenic E. coliPMID 23372726Read ↗

The microbiota metabolite indole inhibits Salmonella virulence: Involvement of the PhoPQ two-component systemSemantic proximity Read ↗

High-Throughput Screen for Novel Antimicrobials using a Whole Animal Infection ModelSemantic proximity Read ↗

The bacterial signalling molecule indole attenuates the virulence of the fungal pathogen Candida albicansSemantic proximity Read ↗

Indole Signaling at the Host-Microbiota-Pathogen InterfaceSemantic proximity Read ↗

Indole Sensing Regulator (IsrR) Promotes Virulence Gene Expression in Enteric PathogensSemantic proximity Read ↗

Microbiota-derived indole limits <i>Campylobacter jejuni</i> colonization by inhibiting respiration and metabolismSemantic proximity Read ↗

The gut microbiota-derived metabolite indole regulates cytoskeletal functions and virulence in <i>Entamoeba histolytica</i>Semantic proximity Read ↗

Pathogenicity and intestinal barrier disruptive ability of <i>Malassezia furfur</i> in an alternative model host <i>Caenorhabditis elegans</i> is partially alleviated by <i>Lacticaseibacillus rhamnosus</i>Semantic proximity Read ↗

Identification of bacterial signals that modulate enteric sensory neurons to influence behavior in C. elegansSemantic proximity Read ↗

Antifungal Chemical Compounds Identified Using a C. elegans Pathogenicity AssaySemantic proximity Read ↗

A Stenotrophomonas maltophilia Strain Evades a Major Caenorhabditis elegans Defense Pathway.Semantic proximity Read ↗

Screening for microbial metabolites affecting phenotype of Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.