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Article

Screening for microbial metabolites affecting phenotype of Caenorhabditis elegans.

Biological & pharmaceutical bulletin - 1 Jan 2011

Yamamuro Daisuke, Uchida Ryuji, Takahashi Yoko, Masuma Rokuro, Tomoda Hiroshi

Abstract excerpt

Microbial samples, including our library of known microbial compounds (ca. 300) and microbial culture broths (ca. 9000), were screened for small molecules affecting the phenotype of Caenorhabditis elegans. As a result, seven known compounds were found to induce phenotypic abnormality of C. elegans. Staurosporine exhibited morphological defects in the vulva and tail of C. elegans, avermectin B1a exhibited hatching...

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PMID: 21963505
DOI: 10.1248/bpb.34.1619

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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