Article
Major variations in Aspergillus fumigatus arising within aspergillomas in chronic pulmonary aspergillosis.
Mycoses - 1 Jul 2013
Howard S J, Pasqualotto A C, Anderson M J, Leatherbarrow H, Albarrag A M, Harrison E, Gregson L, Bowyer P, Denning D W
Abstract excerpt
Aspergillomas develop from progressive layers of mycelial growth on the walls of pulmonary cavities over months. Aspergillomas are characteristic of chronic pulmonary aspergillosis and are a risk factor for azole resistance. We investigated genotypic and phenotypic alterations in Aspergillus fumigatus recovered from aspergillomas. Aspergillomas were removed from three patients (two at surgery, one at autopsy) and...
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