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Antioxidant Intervention Attenuates Aging-Related Changes in the Murine Ovary and Oocyte

22 Oct 2020

Abstract excerpt

Advanced maternal age (AMA) is associated with reduced fertility due in part to diminished ovarian follicle quantity, inferior oocyte quality, chromosome aneuploidy, and lower implantation rates. Ovarian aging is accompanied by increased oxidative stress and blunted antioxidant signaling, such that antioxidant intervention could improve reproductive potential. The first aim of this study was to determine the...

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PMID: 33105678
DOI: 10.3390/life10110250

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