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Article

Delay in oocyte aging in mice by the antioxidant N-acetyl-l-cysteine (NAC)

21 Feb 2012

Abstract excerpt

BACKGROUND: Ovarian aging is associated with declining numbers and quality of oocytes and follicles. Oxidative stress by reactive oxygen species (ROS) contributes to somatic aging in general, and also has been implicated in reproductive aging. Telomere shortening is also involved in aging, and telomeres are particularly susceptible to ROS-induced damage. Previously, we have shown that antioxidant...

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Share to Genetics, Aging, and Longevity in Model Organisms
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PMID: 22357770
DOI: 10.1093/humrep/des019

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