Article
A single-nucleotide polymorphism in SCN9A may decrease postoperative pain sensitivity in the general population.
Anesthesiology - 1 Feb 2013
Duan Guangyou, Xiang Guifang, Zhang Xianwei, Yuan Ruimei, Zhan Huiming, Qi Dongmei
Abstract excerpt
BACKGROUND: This study aimed to explore the role of a nonsynonymous single-nucleotide polymorphism, 3312G>T, in SCN9A, which was identified in probands with congenital indifference to pain, but which is also present in normal controls, in the prediction of individual baseline pain perception, and postoperative pain sensitivity in the general population. METHODS: Preoperative pressure pain thresholds and tolerance...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.