Article
Fine-mapping of 5q12.1-13.3 unveils new genetic contributors to caries.
Caries research - 1 Jan 2013
Shimizu T, Deeley K, Briseño-Ruiz J, Faraco I M, Poletta F A, Brancher J A, Pecharki G D, Küchler E C, Tannure P N, Lips A, Vieira T C S, Patir A, Yildirim M, Mereb J C, Resick J M, Brandon C A, Cooper M E, Seymen F, Costa M C, Granjeiro J M, Trevilatto P C, Orioli I M, Castilla E E, Marazita M L, Vieira A R
Abstract excerpt
Caries is a multifactorial disease and little is still known about the host genetic factors influencing susceptibility. Our previous genome-wide linkage scan has identified the interval 5q12.1-5q13.3 as linked to low caries susceptibility in Filipino families. Here we fine-mapped this region in order to identify genetic contributors to caries susceptibility. Four hundred and seventy-seven subjects from 72...
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