Article
Role of TRAV locus in low caries experience.
Human genetics - 1 Sept 2013
Briseño-Ruiz Jessica, Shimizu Takehiko, Deeley Kathleen, Dizak Piper M, Ruff Timothy D, Faraco Italo M, Poletta Fernando A, Brancher João A, Pecharki Giovana D, Küchler Erika C, Tannure Patricia N, Lips Andrea, Vieira Thays C S, Patir Asli, Koruyucu Mine, Mereb Juan C, Resick Judith M, Brandon Carla A, Letra Ariadne, Silva Renato M, Cooper Margaret E, Seymen Figen, Costa Marcelo C, Granjeiro José M, Trevilatto Paula C, Orioli Iêda M, Castilla Eduardo E, Marazita Mary L, Vieira Alexandre R
Abstract excerpt
Caries is the most common chronic, multifactorial disease in the world today; and little is still known about the genetic factors influencing susceptibility. Our previous genome-wide linkage scan has identified five loci related to caries susceptibility: 5q13.3, 13q31.1, 14q11.2, 14q 24.3, and Xq27. In the present study, we fine mapped the 14q11.2 locus to identify genetic contributors to caries susceptibility....
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