Article
Genetic mapping of high caries experience on human chromosome 13.
BMC medical genetics - 5 Nov 2013
Küchler Erika C, Deeley Kathleen, Ho Bao, Linkowski Samantha, Meyer Chelsea, Noel Jacqueline, Kouzbari M Zahir, Bezamat Mariana, Granjeiro José M, Antunes Leonardo S, Antunes Livia Azeredo, de Abreu Fernanda Volpe, Costa Marcelo C, Tannure Patricia N, Seymen Figen, Koruyucu Mine, Patir Asli, Mereb Juan C, Poletta Fernando A, Castilla Eduardo E, Orioli Ieda M, Marazita Mary L, Vieira Alexandre R
Abstract excerpt
BACKGROUND: Our previous genome-wide linkage scan mapped five loci for caries experience. The purpose of this study was to fine map one of these loci, the locus 13q31.1, in order to identify genetic contributors to caries. METHODS: Seventy-two pedigrees from the Philippines were studied. Caries experience was recorded and DNA was extracted from blood samples obtained from all subjects. Sixty-one single nucleotide...
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