Characterization of the human ABO gene promoter in erythroid cell lineage.

doi:10.1046/j.0042-9007.2001.00134.x

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Article

Characterization of the human ABO gene promoter in erythroid cell lineage.

Vox sanguinis - 1 Jan 2002

Hata Y, Kominato Y, Yamamoto F-I, Takizawa H

Abstract excerpt

BACKGROUND: The human ABO blood group system is important in transfusion and organ transplantation. Although the molecular basis of the ABO gene has been established, recent studies have begun to characterize the mechanism of the ABO gene expression. MATERIALS AND METHODS: Transient transfection assays were carried out in human erythroleukaemia HEL cells and human gastric cancer KATOIII cells. Electrophoretic...

Topics

ABO Blood-Group System
Base Sequence
Binding Sites
Cell Lineage
Electrophoretic Mobility Shift Assay
Erythrocytes
Humans
Molecular Sequence Data
Mutation
Promoter Regions, Genetic
Sp1 Transcription Factor
Tumor Cells, Cultured

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PMID: 11856466
DOI: 10.1046/j.0042-9007.2001.00134.x

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