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Article

Familial liability to psychosis is associated with attenuated dopamine stress signaling in ventromedial prefrontal cortex.

Schizophrenia bulletin - 1 Jan 2014

Lataster Johan, Collip Dina, Ceccarini Jenny, Hernaus Dennis, Haas David, Booij Linda, van Os Jim, Pruessner Jens, Van Laere Koen, Myin-Germeys Inez

Abstract excerpt

OBJECTIVE: Patients diagnosed with a psychotic disorder and their first-degree relatives display increased reactivity to stress. Theory predicts that experience of psychosocial stress is associated both with ventromedial prefrontal and mesolimbic dopamine neurotransmission. However, while there is evidence of aberrant striatal dopamine processing in psychotic disorder, the role of the prefrontal cortex remains...

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Source

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Identifiers

PMID: 23363687
DOI: 10.1093/schbul/sbs187
PMCID: PMC3885294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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