Article
Pituitary volume, stress reactivity and genetic risk for psychotic disorder.
Psychological medicine - 1 Jul 2012
Habets P, Collip D, Myin-Germeys I, Gronenschild E, van Bronswijk S, Hofman P, Lataster T, Lardinois M, Nicolson N A, van Os J, Marcelis M
Abstract excerpt
BACKGROUND: Hypothalamic-pituitary-adrenal (HPA) axis hyperactivity, associated with increased pituitary volume, may mediate observed alterations in stress reactivity in patients with psychotic disorder. We examined the association between pituitary volume, real-life stress reactivity and genetic liability for psychotic disorder. METHOD: Pituitary volumes were derived from magnetic resonance imaging (MRI) scans...
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