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Article

Transportin 1 accumulates in FUS inclusions in adult-onset ALS without FUS mutation.

Neuropathology and applied neurobiology - 1 Aug 2013

Takeuchi R, Toyoshima Y, Tada M, Shiga A, Tanaka H, Shimohata M, Kimura K, Morita T, Kakita A, Nishizawa M, Takahashi H

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23362988
DOI: 10.1111/nan.12022

Genes

FUS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

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Transportin 1 accumulates in FUS inclusions in adult-onset ALS without FUS mutation.PMID 23362988Read ↗

Transportin1: a marker of FTLD-FUSSemantic proximity Read ↗

Transportin 1 accumulates specifically with FET proteins but no other transportin cargos in FTLD-FUS and is absent in FUS inclusions in ALS with FUS mutations.Semantic proximity Read ↗

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Proteomic analysis of FUS interacting proteins provides insights into FUS function and its role in ALSSemantic proximity Read ↗

M6A reduction relieves FUS-associated ALS granules.Semantic proximity Read ↗

Importance of Functional Loss of FUS in FTLD/ALSSemantic proximity Read ↗

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FUS gene mutations associated with familiar forms of amyotrophic lateral sclerosis affect cellular localization and aggregation properties of the encoded protein.Semantic proximity Read ↗

Molecular Determinants and Genetic Modifiers of Aggregation and Toxicity for the ALS Disease Protein FUS/TLSSemantic proximity Read ↗

Expression of human FUS protein in Drosophila leads to progressive neurodegeneration.Semantic proximity Read ↗

ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUSSemantic proximity Read ↗

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