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Article

Functional analysis of genes in regions commonly amplified in high-grade serous and endometrioid ovarian cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Mar 2013

Davis Sally J, Sheppard Karen E, Pearson Richard B, Campbell Ian G, Gorringe Kylie L, Simpson Kaylene J

Abstract excerpt

PURPOSE: Ovarian cancer has the highest mortality rate of all the gynecologic malignancies and is responsible for approximately 140,000 deaths annually worldwide. Copy number amplification is frequently associated with the activation of oncogenic drivers in this tumor type, but their cytogenetic complexity and heterogeneity has made it difficult to determine which gene(s) within an amplicon represent(s) the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to In Situ Hybridization, Fluorescence

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Source

Identifiers

PMID: 23362323
DOI: 10.1158/1078-0432.CCR-12-3433

Genes

GAB2
URI1
PAK4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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