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Article

The role of NADRIN, a Rho GTPase-activating protein, in the morphological differentiation of astrocytes.

Journal of biochemistry - 1 Apr 2013

Kobayashi Yoko, Harada Ayako, Furuta Birei, Asou Hiroaki, Kato Utako, Umeda Masato

Abstract excerpt

Reorganization of the actin cytoskeleton caused by inactivation of the Rho GTPase RhoA is critical for the morphological differentiation of astrocytes into process-bearing stellate cells. The molecular mechanisms underlying the RhoA inactivation and, in particular, the factors that inactivate RhoA, remain to be elucidated. We show here that the expression of a GTPase-activating protein (GAP) for Rho GTPases,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23355722
DOI: 10.1093/jb/mvt005

Genes

ARHGAP17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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