Article
Human growth hormone-variant demonstrates a receptor binding profile distinct from that of normal pituitary growth hormone.
The Journal of biological chemistry - 15 May 1990
Ray J, Okamura H, Kelly P A, Cooke N E, Liebhaber S A
Abstract excerpt
We have recently established that the human growth hormone-variant (hGH-V) gene is functional in vivo by documenting its expression in the placenta. We have subsequently generated transformed murine cell lines stably expressing the genes for normal pituitary growth hormone (hGH-N), hGH-V, and each of two chimeric genes generated by exon 3 exchanges, hGH-NV3 and hGH-VN3. In the present study, we utilize these cell...
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