Article
Human growth hormone-variant demonstrates a receptor binding profile distinct from that of normal pituitary growth hormone.
The Journal of biological chemistry - 15 May 1990
Ray J, Okamura H, Kelly P A, Cooke N E, Liebhaber S A
Abstract excerpt
We have recently established that the human growth hormone-variant (hGH-V) gene is functional in vivo by documenting its expression in the placenta. We have subsequently generated transformed murine cell lines stably expressing the genes for normal pituitary growth hormone (hGH-N), hGH-V, and eac...
Topics
- Amino Acid Sequence
- Animals
- Binding, Competitive
- Cell Line
- DNA, Recombinant
- Genetic Variation
- Growth Hormone
- Humans
- Metallothionein
- Mice
- Microsomes, Liver
- Molecular Sequence Data
- Prolactin
- Promoter Regions, Genetic
- Rabbits
- Rats
- Receptors, Prolactin
- Receptors, Somatotropin