Article
The human placental growth hormone variant is mitogenic for rat lymphoma Nb2 cells.
Endocrinology - 1 Feb 1990
Nickel B E, Kardami E, Cattini P A
Abstract excerpt
Although there is evidence that human (h) placental GH variant (hGH-V) possesses a growth-promoting function, lactogenic activity by the hormone has not been demonstrated. Rat anterior pituitary tumor (GC) cells stably transfected with the hGH-V gene (GC [hGH-V] cells) synthesize and secrete hGH-V. This hormone shares considerable structural similarity with pituitary growth hormone (hGH-N) and chorionic...
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