Article
Insulin receptor substrate 1 (IRS1) variants confer risk of diabetes in the Boston Puerto Rican Health Study.
Asia Pacific journal of clinical nutrition - 1 Jan 2013
Feng Xiang, Tucker Katherine L, Parnell Laurence D, Shen Jian, Lee Yu-Chi, Ordovás José M, Ling Wen-Hua, Lai Chao-Qiang
Abstract excerpt
OBJECTIVE: Published data concerning associations between IRS1 variants and type 2 diabetes and related traits have been inconsistent. We examined the relationship between common variants in IRS1, type 2 diabetes, and related traits including insulin resistance, hyperglycemia and DNA damage in the Boston Puerto Rican Health Study. METHODS: We genotyped six common IRS1 variants in an adult Puerto Rican population...
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