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Article

Models of compensatory molecular evolution: effects of back mutation.

Journal of theoretical biology - 21 Apr 2013

Ichinose Motoshi, Iizuka Masaru, Kusumi Junko, Takefu Masasuke

Abstract excerpt

Compensatory mutations are individually deleterious but appropriate combinations of mutants are harmless. For several models of compensatory molecular evolution, we consider the effects of back mutation. It is shown that the effects of back mutation on the rate of compensatory molecular evolution are weak. Further we estimate the values of selection parameter of deleterious single mutants for the models of...

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PMID: 23353018
DOI: 10.1016/j.jtbi.2013.01.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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