Reversion is most likely under high mutation supply when compensatory mutations do not fully restore fitness costs.

doi:10.1093/g3journal/jkac190

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Article

Reversion is most likely under high mutation supply when compensatory mutations do not fully restore fitness costs.

G3 (Bethesda, Md.) - 25 Aug 2022

Pennings Pleuni S, Ogbunugafor C Brandon, Hershberg Ruth

Abstract excerpt

The dynamics of adaptation, reversion, and compensation have been central topics in microbial evolution, and several studies have attempted to resolve the population genetics underlying how these dynamics occur. However, questions remain regarding how certain features-the evolution of mutators an...

Topics

Adaptation, Physiological
Evolution, Molecular
Genetics, Population
Mutation
Mutation Rate

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