Simulation study of a multigene family, with special reference to the evolution of compensatory advantageous mutations.

doi:10.1093/genetics/132.1.247

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Article

Simulation study of a multigene family, with special reference to the evolution of compensatory advantageous mutations.

Genetics - 1 Sept 1992

Basten C J, Ohta T

Abstract excerpt

We investigate the evolution of a multigene family incorporating the forces of drift, mutation, gene conversion, unequal crossing over and selection. The use of simulation studies is required due to the complexity of the model. Selection is modeled in two modes: positive selection as a function o...

Topics

Alleles
Animals
Biological Evolution
Computer Simulation
Crossing Over, Genetic
Data Interpretation, Statistical
Gene Conversion
Gene Frequency
Models, Genetic
Multigene Family
Mutation
Selection, Genetic

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