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Article

Simulation study of a multigene family, with special reference to the evolution of compensatory advantageous mutations.

Genetics - 1 Sept 1992

Basten C J, Ohta T

Abstract excerpt

We investigate the evolution of a multigene family incorporating the forces of drift, mutation, gene conversion, unequal crossing over and selection. The use of simulation studies is required due to the complexity of the model. Selection is modeled in two modes: positive selection as a function of the number of different beneficial alleles and negative selection against deleterious alleles. We assume that gene...

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Identifiers

PMID: 1398058
DOI: 10.1093/genetics/132.1.247
PMCID: PMC1205123

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