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Article

Phenotypic error threshold; additivity and epistasis in RNA evolution.

BMC evolutionary biology - 3 Feb 2005

Takeuchi Nobuto, Poorthuis Petrus H, Hogeweg Paulien

Abstract excerpt

BACKGROUND: The error threshold puts a limit on the amount of information maintainable in Darwinian evolution. The error threshold was first formulated in terms of genotypes. However, if a genotype-phenotype map involves redundancy ("mutational neutrality"), the error threshold should be formulated in terms of phenotypes since there is no unique fittest genotype. A previous study formulated the error threshold in...

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PMID: 15691379
DOI: 10.1186/1471-2148-5-9
PMCID: PMC550645

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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