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Article

A KCNQ1 mutation causes a high penetrance for familial atrial fibrillation.

Journal of cardiovascular electrophysiology - 1 May 2013

Bartos Daniel C, Anderson Jeffrey B, Bastiaenen Rachel, Johnson Jonathan N, Gollob Michael H, Tester David J, Burgess Don E, Homfray Tessa, Behr Elijah R, Ackerman Michael J, Guicheney Pascale, Delisle Brian P

Abstract excerpt

BACKGROUND: Atrial fibrillation (AF) is the most common cardiac arrhythmia, and its incidence is expected to grow. A genetic predisposition for AF has long been recognized, but its manifestation in these patients likely involves a combination of rare and common genetic variants. Identifying genetic variants that associate with a high penetrance for AF would represent a significant breakthrough for understanding...

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Topics

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Share to Adolescent
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to KCNQ1 Potassium Channel

Share to Long QT Syndrome

Share to Mutation, Missense

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Source

Open in PubMed Open full text

Identifiers

PMID: 23350853
DOI: 10.1111/jce.12068
PMCID: PMC3640728

Genes

KCNQ1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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