Article
Propeptide processing and proteolytic activity of proenzymes of the staphylococcal and enterococcal GluV8-family protease.
Indian journal of biochemistry & biophysics - 1 Dec 2012
Rouf S M A, Ohara-Nemoto Y, Shimoyama Y, Kimura S, Ono T, Nemoto T K
Abstract excerpt
Proenzymes with various lengths of propeptides have been observed in GluV8 from Staphylococcus aureus and GluSE from S. epidermidis. However, the production mechanism of these proenzymes and roles of truncated propeptides have yet to be elucidated. Here we demonstrate that shortening of propeptide commonly occurs in an auto-catalytic manner in GluV8-family members, including those from coagulase negative...
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