Article
Neuronal Goα and CAPS regulate behavioral and immune responses to bacterial pore-forming toxins.
PloS one - 1 Jan 2013
Los Ferdinand C O, Ha Christine, Aroian Raffi V
Abstract excerpt
Pore-forming toxins (PFTs) are abundant bacterial virulence factors that attack host cell plasma membranes. Host defense mechanisms against PFTs described to date all function in the host tissue that is directly attacked by the PFT. Here we characterize a rapid and fully penetrant cessation of feeding of Caenorhabditis elegans in response to PFT attack. We demonstrate via analyses of C. elegans mutants that...
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