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Article

G alphas-induced neurodegeneration in Caenorhabditis elegans.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Apr 1998

Berger A J, Hart A C, Kaplan J M

Abstract excerpt

We describe a genetic model for neurodegeneration in the nematode Caenorhabditis elegans. Constitutive activation of the GTP-binding protein Galphas induces neurodegeneration. Neuron loss occurs in two phases whereby affected cells undergo a swelling response in young larvae and subsequently die...

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PMID: 9526004
PMCID: PMC6792578

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-9526004-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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