Article
Urinary phenotyping indicates weight loss-independent metabolic effects of Roux-en-Y gastric bypass in mice.
Journal of proteome research - 1 Mar 2013
Seyfried Florian, Li Jia V, Miras Alexander D, Cluny Nina L, Lannoo Matthias, Fenske Wiebke K, Sharkey Keith A, Nicholson Jeremy K, le Roux Carel W, Holmes Elaine
Abstract excerpt
Patients with a body mass index (BMI) above 35 kg/m(2) with metabolic diseases benefit from Roux-en-Y gastric bypass (RYGB) independently of their final BMI and the amount of body weight lost. However, the weight loss independent metabolic effects induced by RYGB remain less well understood. To elucidate metabolic changes after RYGB, (1)H NMR spectroscopy-based urine metabolic profiles from RYGB (n = 7), ad...
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