Article
Metabolomic analysis reveals differences in urinary excretion of kiwifruit-derived metabolites in a mouse model of inflammatory bowel disease.
Molecular nutrition & food research - 1 Dec 2011
Lin Hui-Ming, Edmunds Shelley J, Zhu Shuotun, Helsby Nuala A, Ferguson Lynnette R, Rowan Daryl D
Abstract excerpt
The interleukin-10-deficient (IL-10(-/-)) mouse, a model of inflammatory bowel disease (IBD), develops intestinal inflammation unless raised in germ-free conditions. The metabolic effects of consuming extracts from the fruits of yellow (Actinidia chinensis) or green-fleshed (A. deliciosa) kiwifruit that displayed in vitro anti-inflammatory activity were investigated in IL-10(-/-) mice by metabolomic analysis of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.