Article
Metabolic phenotype-microRNA data fusion analysis of the systemic consequences of Roux-en-Y gastric bypass surgery.
International journal of obesity (2005) - 1 Jul 2015
Wu Q, Li J V, Seyfried F, le Roux C W, Ashrafian H, Athanasiou T, Fenske W, Darzi A, Nicholson J K, Holmes E, Gooderham N J
Abstract excerpt
BACKGROUND/OBJECTIVES: Bariatric surgery offers sustained marked weight loss and often remission of type 2 diabetes, yet the mechanisms of establishment of these health benefits are not clear. SUBJECTS/METHODS: We mapped the coordinated systemic responses of gut hormones, the circulating miRNAome and the metabolome in a rat model of Roux-en-Y gastric bypass (RYGB) surgery. RESULTS: The response of circulating...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.