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Article

Involvement of IL-9 in Th17-associated inflammation and angiogenesis of psoriasis.

PloS one - 1 Jan 2013

Singh Tej Pratap, Schön Michael P, Wallbrecht Katrin, Gruber-Wackernagel Alexandra, Wang Xiao-Jing, Wolf Peter

Abstract excerpt

It is thought that a Th1/Th17-weighted immune response plays a predominant role in the pathogenesis of psoriasis. Our findings now indicate a link between IL-9, a Th2 and Th9 cytokine, and Th17 pathway in psoriasis. In K5.hTGF-β1 transgenic mice, exhibiting a psoriasis-like phenotype, we found increased IL-9R and IL-9 expression in the skin and intradermal IL-9 injection induced Th17-related inflammation. IL-9...

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Share to Antibodies, Monoclonal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neovascularization, Pathologic

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Source

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Identifiers

PMID: 23335955
DOI: 10.1371/journal.pone.0051752
PMCID: PMC3546056

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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