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Article

Activin A and TGF-β promote T(H)9 cell-mediated pulmonary allergic pathology.

The Journal of allergy and clinical immunology - 1 Apr 2012

Jones Carla P, Gregory Lisa G, Causton Benjamin, Campbell Gaynor A, Lloyd Clare M

Abstract excerpt

BACKGROUND: IL-9-secreting (T(H)9) T cells are thought to represent a distinct T-cell subset. However, evidence for their functionality in disease is uncertain. OBJECTIVE: To define a functional phenotype for T(H)9-driven pathology in vivo. METHODS: We used fluorescence-activated cell sorting to identify circulating T(H)9 cells in atopic and nonatopic subjects. In mice we utilized a model of allergic airways...

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Source

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Identifiers

PMID: 22277204
DOI: 10.1016/j.jaci.2011.12.965
PMCID: PMC3385370

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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