Article
TH9 cells are required for tissue mast cell accumulation during allergic inflammation.
The Journal of allergy and clinical immunology - 1 Aug 2015
Sehra Sarita, Yao Weiguo, Nguyen Evelyn T, Glosson-Byers Nicole L, Akhtar Nahid, Zhou Baohua, Kaplan Mark H
Abstract excerpt
BACKGROUND: IL-9 is important for the growth and survival of mast cells. IL-9 is produced by T cells, natural killer T cells, mast cells, eosinophils, and innate lymphoid cells, although the cells required for mast cell accumulation during allergic inflammation remain undefined. OBJECTIVE: We sought to elucidate the role of TH9 cells in promoting mast cell accumulation in models of allergic lung inflammation....
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