The tandem β-zipper: modular binding of tandem domains and linear motifs.

Abstract excerpt

The tandem β-zipper protein-protein binding interface involves an intrinsically disordered protein (IDP) binding two or more globular domains through β-sheet-augmentation in a modular fashion, and represents a paradigm in IDP-mediated protein-protein interactions. While characterised tandem β-zippers are rare, known examples are associated with diverse biological processes. A combination of their advantages...

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