Article
A poor metabolizer of both CYP2C19 and CYP2D6 identified by mechanistic pharmacokinetic simulation in a fatal drug poisoning case involving venlafaxine.
Forensic science international - 10 Mar 2013
Jornil J, Nielsen T S, Rosendal I, Ahlner J, Zackrisson A L, Boel L W T, Brock B
Abstract excerpt
We present a fatal drug poisoning case involving venlafaxine (VEN). The deceased took his medication regularly (including 150 mg VEN twice daily), and nothing in the case or autopsy findings pointed towards suicide. The toxicological assessment concluded that the cause of death was most likely due to a poisoning with a combination of VEN, oxycodone and ethanol, and the manner of death was considered to be an...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
